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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLXIPL All Species: 9.39
Human Site: S59 Identified Species: 15.9
UniProt: Q9NP71 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NP71 NP_116569.1 852 93073 S59 F M V S S P H S D S L P R R R
Chimpanzee Pan troglodytes XP_509441 819 90122 N48 L V S P K W K N F K G L K L Q
Rhesus Macaque Macaca mulatta XP_001115131 390 43669
Dog Lupus familis XP_546925 857 93734 S59 F M V S S P H S D S L P R R R
Cat Felis silvestris
Mouse Mus musculus Q99MZ3 864 94857 S59 F M V S S P H S D S L T R R R
Rat Rattus norvegicus Q6AXT8 471 49872
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001104311 895 97370 P60 G H F M V S S P H H D A L P H
Frog Xenopus laevis NP_001084764 548 60887
Zebra Danio Brachydanio rerio XP_001338503 817 90800 F63 P P K K G Y D F D T V N K Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_724328 836 92381 L63 D L I P T T R L P P V P E E G
Honey Bee Apis mellifera XP_394429 1014 115124 P81 V K V A I I T P P G L S H E K
Nematode Worm Caenorhab. elegans P41846 1009 112841 N52 S S S V H H K N K A L D E K P
Sea Urchin Strong. purpuratus XP_788672 1338 148936 K69 F M V S N P H K V K K S G G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LVN1 1266 139556 S60 E H F P E A S S L V F N F R E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.6 42.9 87.7 N.A. 81.4 20.8 N.A. N.A. 51.4 30.9 39.4 N.A. 20 29.5 25.5 21.1
Protein Similarity: 100 55.4 43.9 91.4 N.A. 85.7 29.3 N.A. N.A. 60.7 41.6 53.5 N.A. 36.5 44.9 41.3 33.5
P-Site Identity: 100 0 0 100 N.A. 93.3 0 N.A. N.A. 0 0 6.6 N.A. 6.6 13.3 6.6 40
P-Site Similarity: 100 26.6 0 100 N.A. 93.3 0 N.A. N.A. 0 0 33.3 N.A. 33.3 26.6 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 34 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 29 0 8 8 0 0 0 % D
% Glu: 8 0 0 0 8 0 0 0 0 0 0 0 15 15 8 % E
% Phe: 29 0 15 0 0 0 0 8 8 0 8 0 8 0 0 % F
% Gly: 8 0 0 0 8 0 0 0 0 8 8 0 8 8 8 % G
% His: 0 15 0 0 8 8 29 0 8 8 0 0 8 0 8 % H
% Ile: 0 0 8 0 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 8 8 8 0 15 8 8 15 8 0 15 8 8 % K
% Leu: 8 8 0 0 0 0 0 8 8 0 36 8 8 8 0 % L
% Met: 0 29 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 15 0 0 0 15 0 0 0 % N
% Pro: 8 8 0 22 0 29 0 15 15 8 0 22 0 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 22 29 22 % R
% Ser: 8 8 15 29 22 8 15 29 0 22 0 15 0 0 0 % S
% Thr: 0 0 0 0 8 8 8 0 0 8 0 8 0 0 8 % T
% Val: 8 8 36 8 8 0 0 0 8 8 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _